To draw upon the well-established insight "Mens sana in corpore sano": A healthy mind rests in a healthy body. But did you know that your muscles can communicate? Think of your muscles as diligent postmen delivering important messages about your health. These chemical messages, known as myokines, unfold diverse health benefits and lie at the center of groundbreaking health research. Let us delve together into the fascinating world of myokines and discover how they can enhance your well-being.

Myokines are signaling molecules proteinslarge, complex molecules made of amino acids that are released during muscle contraction. These messages exert effects on various organs in the body and play a key role in regulating metabolic processes and inflammation. Essentially, myokines function like biochemical guides emitted by our muscles to maintain the body in balance. Let’s think of them as the body's email, sending messages to different recipients such as the brain, liver, or adipose tissue.

The release of myokines has significant implications for health and well-being. For example, they promote metabolismall chemical reactions in the body that produce energy, strengthen the immune system, and improve cardiovascular health. Particular emphasis is placed on their role in combating inflammation, often associated with chronic diseases such as type 2 diabetes and heart disease. Myokines are integral agents that can reduce or slow the onset of such diseases.

The diversity and significance of myokines are examined for example. in a study investigating the effects of endurance and strength training on myokines and metabolism in women with type 2 diabetes ^[1]. This randomized study involving 52 participants showed that while training improved aerobic capacity and blood sugar levelsamount of sugar in the blood, it had no significant impact on the quantities of measured myokines. However, the study confirms the positive effects of exercise on the overall health status of diabetics, supporting the hypothesis that a change in myokine production can be grossly overestimated if the timing of training is not optimally chosen. Nevertheless, there are several other studies supporting the positive effects of especially strength training in the context of myokine production. After all, the relevance of myokines should continue to be explored in long-term studies to fully understand their clinical significance.

To maximize the health-promoting effects of myokines, combine endurance and strength training. This combination optimizes muscle activity and amplifies the effects of myokines. Fitness routines can therefore include a mix of running, cycling, and functional weight training. The study indicates that regular physical activity offers extensive benefits, even if the effects on myokine levels may vary. A balanced diet complements these efforts to support metabolism and promote overall health.

Myokines are more than just byproducts of muscular exertion. They are crucial health ambassadors that help our bodies stay healthy. Through regular exercise, we can activate these molecular helpers and thus strengthen our overall health. Put on your workout gear and experience how your muscles become your health allies!